Ozone Sterilization of Bone Grafts


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Membership level
2011-2012 Team
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Team Name
Project Title
Ozone Sterilization of Bone Grafts
Design Challenge
Over half of surgeons have witnessed a bone graft being dropped outside of the sterile field during surgery, resulting in the contamination of the graft. While current re-sterilization techniques successfully eliminate pathogenic contaminants, they require time-consuming operation cycles and damage native cells and proteins.

Ozone gas can be applied to sterilize contaminated tissue grafts, protect the viability of native cells found on the graft’s surface, and eliminate all infectious pathogens on the surface. We are designing a device that accurately and rapidly generates and applies gaseous ozone to bone grafts for decreased risks of infection and immunological responses to implanted bone grafts.
Design Summary
Our device is capable of re-sterilizing contaminated orthopedic grafts directly in the operating room (OR) during surgery using gaseous ozone. To accomplish this goal and ensure user safety, the device reliably delivers specified ozone concentrations within a contained chamber and minimizes leakage. Additionally, the device features a fast sterilization cycle, holds orthopedic grafts of various sizes, is portable, intuitive to use, and affordable for hospitals.

Updated: 04/30/12
OEDK and the Rice BIOE Department
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  • Bioengineering
Faculty Advisor 1 - Name
Ann Saterbak

Team Members

Award(s) and Recognition
2012 Engineering Design Showcase: Best Design for Research

Contact us

Oshman Engineering Design Kitchen
Rice University

6100 Main Street MS 390 | Houston, Texas | 77005

Phone: 713.348.OEDK

Email: oedk@rice.edu

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